Nuclear localisation signal search
PredictNLS is an automated tool for the analysis and determination of Nuclear Localization Signals (NLS). You submit a protein sequence or a potential NLS. PredictNLS predicts that your protein is nuclear or finds out whether your potential NLS is found in our database.Nov 01, 2000 Simplification of nuclear import. A nuclear localization signal (NLS) is a short stretch of amino acids that mediates the transport of nuclear proteins into the nucleus (Figure 1). nuclear localisation signal search
Nov 15, 2000 Simplification of nuclear import. A nuclear localization signal (NLS) is a short stretch of amino acids that mediates the transport of nuclear proteins into the nucleus (Figure (Figure1). 1 ). NLS motifs play a key role in this mechanism; (i) typically, deletion
Jan 01, 2003 Format and fields. NLSdb has been formated in an EMBLlike flatfile format, thus allowing indexing of the database in SRS ( 8 ). Each NLSdb entry describes a nuclear localization signal. Each entry is organized into six major fields; (i) Origin; (ii) Annotation; (iii) Reference; (iv) Confidence; (v) Proteins; and (vi) DNA binding. SeqNLS: Nuclear localization signal prediction based on frequent pattern mining and linear motif scoring. Citation: JhihRong Lin and Jianjun Hu. SeqNLS: Nuclear localization signal prediction based onnuclear localisation signal search The Nuclear Protein Database (NPD) Subnuclear localization and functional annotation of the nuclear proteome Search for information on proteins that are localized to the nucleus of vertebrate cells.
Mar 01, 2007 Abstract. Summary: NucPred analyzes patterns in eukaryotic protein sequences and predicts if a protein spends at least some time in the nucleus or no time at all. Subcellular location of proteins represents functional information, which is important for understanding protein interactions, for the diagnosis of human diseases and for drug discovery. nuclear localisation signal search How can the answer be improved? I am looking at a mutations in a nuclear localization signal (NLS) and I am wondering if I can inhibit nuclear import in a cell culture somehow. Dawid Walas Hi there, Feb 23, 2007 Search by Keyword Author Year Vol Page Advanced Search a protein containing a classical basic nuclear localization signal (NLS) is imported by a heterodimeric import receptor consisting of the karyopherin importin, which mediates interactions with the nuclear pore complex, and the adaptor protein importin, which directly binds the Nuclear localization sequence topic. A nuclear localization signal or sequence ( NLS ) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport. Typically, this signal consists of one or more short sequences of positively charged lysines orRating: 4.56 / Views: 871